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Writer's pictureMaureen Harrop

Serotonin & Stroke

A stroke occurs when blood flow to a part of the brain is interrupted, either due to a blockage (ischemic stroke) or bleeding (hemorrhagic stroke). Serotonin is a neurotransmitter that plays a role in various bodily functions, including mood regulation, sleep, and appetite. While strokes primarily affect the brain's blood vessels and oxygen supply, they can also influence neurotransmitter levels, including serotonin.


The impact of a stroke on serotonin levels can be complex and multifaceted:

  • Brain damage: A stroke can cause damage to brain tissue due to lack of oxygen and nutrients. This damage can affect the neurons responsible for producing and regulating serotonin, potentially leading to alterations in serotonin levels.

  • Neurotransmitter imbalance: Disruption of the brain's normal functioning due to a stroke can result in imbalances in neurotransmitters, including serotonin. Changes in serotonin levels may contribute to mood changes, emotional disturbances, or cognitive impairments experienced by stroke survivors.

  • Secondary effects: Strokes can lead to various complications, such as depression, anxiety, or changes in behavior. Serotonin is closely linked to mood regulation, and alterations in its levels can contribute to mood disorders that may arise after a stroke.

  • Medications and treatments: Patients who have suffered a stroke may be prescribed medications or therapies that directly or indirectly affect serotonin levels. For example, antidepressants targeting serotonin reuptake (selective serotonin reuptake inhibitors, SSRIs) might be prescribed to manage post-stroke depression or mood disturbances.


Note: Naturopaths have excellent natural supplements & remedies for replacing these deficiencies. Or, one can choose the chemical drug route


Overall, strokes can have diverse effects on the brain and its neurotransmitter systems, including serotonin. The extent of impact on serotonin levels can vary widely among individuals based on the location, severity, and type of stroke, as well as other individual factors. Monitoring and managing neurotransmitter levels, including serotonin, can be an important aspect of stroke recovery and management of associated conditions like mood disorders or cognitive changes.

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